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Introduction
VONOSTRUM 10, containing Vonoprazan 10 mg, is a next-generation acid suppressant medication used to treat acid-related gastrointestinal disorders. Unlike traditional proton pump inhibitors (PPIs), Vonoprazan belongs to a newer class known as Potassium-Competitive Acid Blockers (P-CABs), offering faster, longer, and more consistent acid suppression.
Manufactured under high-quality standards by Steris Healthcare Pvt. Ltd., Vonoprazan 10 mg tablet offers enhanced stability and better symptom control in acid-peptic conditions compared to conventional therapies.
Composition
- Active Ingredient: Vonoprazan 10 mg
- Formulation Type: Oral tablet
- Route of Administration: Oral
- Packaging: Available in blister or strip form
Medical Uses of Vonoprazan 10 mg (VONOSTRUM 10)
VONOSTRUM 10 is used for the management of:
- Gastroesophageal Reflux Disease (GERD)
- Erosive Esophagitis
- Peptic Ulcer Disease (gastric & duodenal ulcers)
- H. pylori Eradication Therapy (in combination with antibiotics)
- NSAID-Induced Gastric Ulcers
- Zollinger-Ellison Syndrome and other hypersecretory conditions
How Vonoprazan Works
Vonoprazan competitively inhibits the potassium-binding site of H⁺/K⁺-ATPase (the proton pump) in gastric parietal cells. This blocks acid secretion more rapidly and effectively than PPIs, with a longer duration of action and no need for acid activation.
Dosage & Administration
- Typical Adult Dose:
10 mg once daily, usually before meals
(May be increased to 20 mg in severe cases or based on clinical need) - Duration of Therapy:
Ranges from 2 to 8 weeks, depending on the condition (e.g., GERD or ulcer)
Note: Dosage may vary for H. pylori eradication where it is combined with antibiotics like amoxicillin and clarithromycin.
Side Effects of Vonoprazan 10 mg
Most patients tolerate VONOSTRUM 10 well. However, some may experience:
Common Side Effects
- Headache
- Constipation
- Diarrhea
- Abdominal discomfort
- Nausea
Rare but Serious Side Effects
- Liver enzyme elevation
- Hypomagnesemia (with long-term use)
- Rash or allergic reactions
Always consult your physician if you experience persistent or unusual symptoms.
Why Choose VONOSTRUM 10 by Steris Healthcare?
- Faster Symptom Relief: Rapid onset of acid suppression compared to PPIs
- Stable in Acidic Environment: No requirement for activation in acidic pH
- WHO-GMP Certified Manufacturing: Ensures purity, potency, and patient safety
- Improved Patient Compliance: Once-daily dosing and fewer food-related restrictions
- Backed by a Reputed Brand: Manufactured by Steris Healthcare Pvt. Ltd., known for premium-quality, affordable pharmaceuticals
Frequently Asked Questions (FAQs)
Q1: Is Vonoprazan better than traditional PPIs like omeprazole or pantoprazole?
A: Yes. Vonoprazan offers faster and more consistent acid suppression, works independently of food intake, and provides longer-lasting relief.
Q2: Can I take Vonoprazan 10 mg with food?
A: Yes. Vonoprazan can be taken with or without food, unlike PPIs which must be taken before meals.
Q3: Is VONOSTRUM 10 safe for long-term use?
A: It is generally safe under medical supervision. For chronic conditions, periodic monitoring is advised.
Q4: Can VONOSTRUM 10 be used in children?
A: It is primarily approved for adult use. Pediatric usage should be guided by a specialist.
Q5: What should I avoid while taking Vonoprazan?
A: Avoid alcohol, tobacco, and NSAIDs unless prescribed, as they may aggravate acid production.
Conclusion
VONOSTRUM 10 (Vonoprazan 10 mg Tablet) represents a significant advancement in the treatment of acid-related gastrointestinal disorders. With its rapid onset, superior acid control, and convenient once-daily dosing, it outperforms many traditional PPIs. Manufactured by Steris Healthcare Pvt. Ltd., it meets high standards of quality, making it a reliable and effective choice for patients and healthcare providers alike.
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