Medicine information
उपयोग
CARDULES ISMN SR 30 by Steris Healthcare contains 30 mg of Isosorbide Mononitrate in a specialized Sustained Release (SR) formulation. Designed for extended cardiac protection, this oral organic nitrate delivers a controlled release of the active medication over several hours, maintaining steady therapeutic blood levels to prevent exertional and vasospastic chest pain while guarding against nitrate tolerance. Key Uses & Clinical Benefits: Angina Pectoris Prevention: Effectively reduces the frequency, duration, and severity of chronic stable chest pain episodes caused by narrowed coronary arteries. Sustained Release Technology: Designed to release the drug continuously over an extended period, ensuring stable hemodynamic coverage and preventing sudden spikes or drops in medication levels. Reduces Myocardial Workload: Dilates peripheral veins and arteries, reducing pre-load and systemic vascular resistance (afterload), which decreases the heart's oxygen demand. Prevents Nitrate Tolerance: Formulated to provide an eccentric dosing schedule that maintains an essential daily "nitrate-free interval," preventing the vascular tolerance commonly associated with traditional nitrate therapy. Improves Exercise Tolerance: Allows patients with chronic stable angina to engage in daily activities and light exercise with decreased chest discomfort. How CARDULES ISMN SR 30 Works: Isosorbide Mononitrate is metabolized to produce Nitric Oxide (NO) in vascular smooth muscle. Nitric oxide activates guanylate cyclase, increasing intracellular cyclic Guanosine Monophosphate (cGMP). This leads to vascular smooth muscle relaxation, causing prominent venous dilation, reduced cardiac preload, and improved blood flow through collateral coronary channels.
कैसे उपयोग करें
Take 1 tablet of CARDULES ISMN SR 30 once daily in the morning, or strictly as directed by your cardiologist or physician. Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet, as this destroys the sustained-release mechanism. Take the dose consistently at the same time every morning to ensure an optimal drug-free interval during rest/sleep.
भंडारण
Store in a cool, dry, and dark place away from direct sunlight, heat, and moisture. Maintain at a controlled room temperature below 30°C. Keep out of reach and sight of children.
