Medicine information
उपयोग
GLISITAPTIN M 1000 by Steris Healthcare combines two complementary blood sugar-lowering agents: Sitagliptin Phosphate (50 mg) and Metformin Hydrochloride (1000 mg). By pairing a selective DPP-4 inhibitor with a higher strength of biguanide, this dual-combination therapy addresses multiple metabolic defects in type 2 diabetes—enhancing glucose-dependent insulin release and significantly improving peripheral insulin sensitivity. Key Uses & Clinical Benefits: Synergistic Glycemic Regulation: Effectively lowers both fasting and postprandial (post-meal) blood glucose levels, helping patients reach and maintain target HbA1c goals. Incretin Enhancement: Sitagliptin (a DPP-4 inhibitor) prolongs the active life of naturally occurring incretin hormones (GLP-1 and GIP), boosting natural insulin secretion in response to food while suppressing excessive glucagon release. Reduces Hepatic Glucose Output: Metformin decreases glucose production in the liver, reduces intestinal glucose absorption, and enhances peripheral tissue sensitivity to insulin. Low Risk of Hypoglycemia: Works primarily through glucose-dependent mechanisms, providing high therapeutic safety and a low risk of low blood sugar spikes when used as directed. Weight-Neutral & Metabolic Support: Delivers comprehensive blood sugar management without causing body weight gain, supporting long-term metabolic and cardiovascular health. How GLISITAPTIN M 1000 Works: Sitagliptin Phosphate (50 mg): Prevents the enzymatic breakdown of incretin hormones by DPP-4, increasing mealtime insulin production and curbing excess glucagon output. Metformin Hydrochloride (1000 mg): Activates AMP-activated protein kinase (AMPK) in liver tissue to suppress gluconeogenesis and optimize cellular response to circulating insulin.
कैसे उपयोग करें
Take 1 tablet of GLISITAPTIN M 1000 twice daily with meals (preferably with breakfast and dinner) or strictly as prescribed by your physician. Taking the tablet with food helps reduce potential gastrointestinal upset associated with Metformin. Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet.
भंडारण
Store in a cool, dry place away from direct sunlight, light, and moisture. Store at a controlled room temperature below 30°C. Keep out of reach and sight of children.
