Medicine information
उपयोग
GLISITAPTIN M KIT by Steris Healthcare delivers a powerful, high-potency combination of two proven antidiabetic agents: Sitagliptin Phosphate (100 mg) and Metformin Hydrochloride (1000 mg). Designed for adult patients requiring intensive glycemic regulation, this dual-action kit targets multiple pathophysiological pathways in type 2 diabetes—boosting glucose-dependent insulin secretion and overcoming peripheral insulin resistance. Key Uses & Clinical Benefits: Maximum Glycemic Control: Combines full clinical strengths of Sitagliptin and Metformin to effectively lower both fasting and postprandial (post-meal) blood glucose levels, helping patients reach difficult HbA1c goals. Incretin Enhancement: Sitagliptin (a selective DPP-4 inhibitor) prolongs the active life of naturally occurring incretin hormones (GLP-1 and GIP), enhancing natural insulin secretion after meals while suppressing inappropriate glucagon release. Reduces Hepatic Glucose Output: Metformin decreases gluconeogenesis and glycogenolysis in the liver, reduces intestinal glucose absorption, and increases peripheral tissue sensitivity to circulating insulin. Low Risk of Hypoglycemia: Works via glucose-dependent pathways, providing high therapeutic safety without causing sudden sugar drops when used as monotherapy alongside Metformin. Weight-Neutral & Metabolic Support: Offers comprehensive blood sugar management without causing body weight gain, supporting long-term metabolic and cardiovascular health. How GLISITAPTIN M KIT Works: Sitagliptin Phosphate (100 mg): Prevents the rapid degradation of incretin hormones by inhibiting the DPP-4 enzyme, increasing mealtime insulin synthesis and lowering excess post-meal glucagon. Metformin Hydrochloride (1000 mg): Activates AMP-activated protein kinase (AMPK) in liver tissue to suppress gluconeogenesis and optimize peripheral cellular glucose utilization.
कैसे उपयोग करें
Take 1 dose of GLISITAPTIN M KIT once or twice daily with meals (preferably with breakfast or dinner) or strictly as prescribed by your physician. Taking the medication with food minimizes potential gastrointestinal side effects associated with Metformin. Swallow the tablets whole with a glass of water. Do not crush, chew, or break the tablets.
भंडारण
Store in a cool, dry place away from direct sunlight, light, and moisture. Store at a controlled room temperature below 30°C. Keep out of reach and sight of children.
