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Made by SterisWHO-GMP

Seizmet Sr 850

by Steris Healthcare Pvt. Ltd.

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Metformin Hydrochloride 850 mg

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ManufacturerSteris Healthcare Pvt. Ltd.
Manufacturing qualityWHO-GMP verified
Expiry policyMinimum 3 months
ReviewedClinical review pending

Medicine information

उपयोग

SEIZMET SR 850 by Steris Healthcare provides 850 mg of Metformin Hydrochloride in an advanced Sustained Release (SR) matrix. As the foundation of modern type 2 diabetes management, SEIZMET SR 850 enhances the body's natural sensitivity to insulin, lowers hepatic glucose production, and ensures steady, round-the-clock blood sugar control without overburdening pancreatic beta-cells. Key Uses & Clinical Benefits: Optimal Glycemic Regulation: Effectively lowers both fasting and postprandial (post-meal) blood glucose levels, helping patients reach and maintain target HbA1c goals. Reduces Hepatic Glucose Output: Inhibits gluconeogenesis and glycogenolysis in liver tissue, preventing excess glucose production during periods of fasting. Enhances Insulin Sensitivity: Increases peripheral tissue (skeletal muscle and fat) responsiveness to circulating insulin, improving cellular glucose uptake and utilization. Sustained-Release Matrix: The controlled-release 850 mg dosage ensures gradual active ingredient release throughout the gastrointestinal tract, significantly minimizing common stomach upset, cramps, and nausea compared to immediate-release formulations. Weight-Neutral & Cardiovascular Support: Does not promote weight gain and supports favorable lipid profiles, contributing to long-term metabolic and cardiovascular wellness. Low Risk of Monotherapy Hypoglycemia: Works by improving glucose tolerance without directly stimulating insulin secretion, making blood sugar crashes extremely rare when used alone. How SEIZMET SR 850 Works: Metformin activates AMP-activated protein kinase (AMPK) in hepatic cells, suppressing glucose synthesis in the liver. Additionally, it delays intestinal absorption of glucose and enhances insulin receptor sensitivity in peripheral tissues to optimize overall cellular glucose clearance.

कैसे उपयोग करें

Take 1 tablet of SEIZMET SR 850 once or twice daily with meals (preferably during or immediately after breakfast/evening meal) or strictly as prescribed by your physician. Taking the tablet with food minimizes potential gastrointestinal side effects. Swallow the tablet whole with a full glass of water—do not crush, chew, or break the tablet, as doing so destroys the sustained-release mechanism.

भंडारण

Store in a cool, dry place away from direct sunlight, light, and moisture. Store at a controlled room temperature below 30°C. Keep out of reach and sight of children.

Important guidance

Safety advice

Check with your doctor
AlcoholConsult your doctor

Avoid alcohol consumption while taking SEIZMET SR 850, as excessive intake significantly increases the risk of Metformin-associated lactic acidosis and unpredictable blood sugar drops.

PregnancyConsult your doctor

Consult your doctor before using SEIZMET SR 850 during pregnancy. While Metformin is sometimes used under specialist care, insulin is generally preferred for blood sugar management in pregnancy.

BreastfeedingConsult your doctor

Do not use SEIZMET SR 850 while breastfeeding without medical evaluation, as Metformin passes into human breast milk.

DrivingConsult your doctor

SEIZMET SR 850 alone does not cause hypoglycemia or impair alertness, making it safe for driving and operating machinery.

KidneyConsult your doctor

Contraindicated in severe renal impairment (eGFR < 30 mL/min/1.73 m²). Kidney function tests should be evaluated prior to initiating treatment and monitored regularly.

LiverConsult your doctor

Avoid use in patients with clinical or laboratory evidence of hepatic impairment due to the increased risk of lactic acidosis associated with Metformin clearance.

Clinical review pending

This page uses verified catalogue facts and responsible medicine-information rules. It supports awareness and does not replace a doctor's advice.

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