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Made by SterisWHO-GMP

Vildiabate M 500

by Steris Healthcare Pvt. Ltd.

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Vildagliptin 50 mg + Metformin Hydrochloride 500 mg

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ManufacturerSteris Healthcare Pvt. Ltd.
Manufacturing qualityWHO-GMP verified
Expiry policyMinimum 3 months
ReviewedClinical review pending

Medicine information

उपयोग

VILDIABATE M 500 by Steris Healthcare brings together two complementary blood sugar-lowering agents: Vildagliptin (50 mg) and Metformin Hydrochloride (500 mg). By combining a potent DPP-4 inhibitor with a biguanide, this dual-action formulation targets type 2 diabetes through two distinct, synergistic pathways—enhancing glucose-dependent insulin secretion and overcoming peripheral insulin resistance. Key Uses & Clinical Benefits: Synergistic Glycemic Regulation: Effectively lowers both fasting and postprandial (post-meal) blood glucose levels, helping patients achieve and sustain target HbA1c goals. Incretin Enhancement: Vildagliptin (a DPP-4 inhibitor) prevents the rapid breakdown of incretin hormones (GLP-1 and GIP), boosting natural mealtime insulin release while suppressing excessive glucagon secretion. Reduces Hepatic Glucose Output: Metformin decreases glucose synthesis in the liver, reduces intestinal glucose absorption, and improves peripheral tissue sensitivity to circulating insulin. Low Risk of Hypoglycemia: Works primarily through glucose-dependent mechanisms, resulting in a low risk of low blood sugar spikes when used as directed. Weight-Neutral & Metabolic Support: Delivers comprehensive blood sugar management without causing body weight gain, supporting long-term metabolic health. How VILDIABATE M 500 Works: Vildagliptin (50 mg): Selectively inhibits the DPP-4 enzyme, raising active incretin hormone levels to stimulate pancreatic insulin output and inhibit inappropriate glucagon secretion in response to meals. Metformin Hydrochloride (500 mg): Activates AMP-activated protein kinase (AMPK) in liver tissue to suppress gluconeogenesis and enhance cellular glucose uptake in muscle cells.

कैसे उपयोग करें

Take 1 tablet of VILDIABATE M 500 twice daily with meals (preferably with breakfast and dinner) or strictly as prescribed by your physician. Taking the medication with food helps minimize potential gastrointestinal discomfort associated with Metformin. Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet.

भंडारण

Store in a cool, dry place away from direct sunlight, light, and moisture. Store at a controlled room temperature below 30°C. Keep out of reach and sight of children.

Important guidance

Safety advice

Check with your doctor
AlcoholConsult your doctor

Avoid drinking alcohol while taking VILDIABATE M 500, as excessive intake increases the risk of Metformin-associated lactic acidosis and unpredictable blood sugar fluctuations.

PregnancyConsult your doctor

VILDIABATE M 500 is generally not recommended during pregnancy. Consult your healthcare provider for safer alternatives, such as insulin therapy.

BreastfeedingConsult your doctor

Do not use VILDIABATE M 500 while breastfeeding without medical evaluation, as Metformin and Vildagliptin components may pass into human breast milk.

DrivingConsult your doctor

VILDIABATE M 500 alone usually does not cause hypoglycemia. However, exercise caution if taken in combination with sulfonylureas or insulin, as low blood sugar may affect your ability to drive.

KidneyConsult your doctor

Contraindicated in severe renal impairment (eGFR < 30 mL/min/1.73 m²). Renal function should be evaluated prior to starting treatment and monitored regularly.

LiverConsult your doctor

Not recommended for patients with hepatic impairment or elevated baseline liver enzymes (ALT/AST). Periodic liver function tests (LFTs) are recommended during therapy.

Clinical review pending

This page uses verified catalogue facts and responsible medicine-information rules. It supports awareness and does not replace a doctor's advice.

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