Medicine information
Uses & overview
CONARIS SB 130 by Steris Healthcare contains 130 mg of Itraconazole formulated with Super Bioavailable (SB) technology. Standard Itraconazole formulations suffer from erratic gastric absorption and depend heavily on stomach acid and food intake. CONARIS SB 130 overcomes these limitations by delivering enhanced aqueous solubility and predictable systemic bioavailability, allowing for lower dosing while maintaining high drug concentrations in target tissues like skin, nails, and mucous membranes. Key Ingredients & Clinical Benefits: Itraconazole SB (130 mg): A potent broad-spectrum triazole antifungal that inhibits the fungal cytochrome P450-dependent enzyme 14$\alpha$-demethylase. This blocks the conversion of lanosterol to ergosterol—an essential component of the fungal cell membrane—leading to membrane disruption, increased permeability, and fungal cell death. Key Uses & Clinical Benefits: Super Bioavailable Technology: Delivers therapeutic tissue levels comparable to higher doses of conventional Itraconazole (e.g., 200 mg), offering higher efficacy with lower drug load. Gastric Acid Independent Absorption: Unlike traditional Itraconazole, SB technology allows consistent absorption regardless of stomach acidity or concurrent antacid use. Broad-Spectrum Antifungal Coverage: Highly effective against dermatophytes (Tinea corporis, Tinea cruris, Tinea pedis), yeasts (Candida species), and systemic fungi (Aspergillus, Blastomyces, Histoplasma). Treatment of Recalcitrant Dermatophytosis: Ideal for hard-to-treat, chronic, or recurrent fungal skin infections and severe nail fungal infections (onychomycosis). High Tissue Affinity: Accumulates in keratin-rich tissues (skin, hair, and nails) where it remains active long after the treatment course is completed.
How to use
Take 1 capsule of CONARIS SB 130 once or twice daily, or strictly as prescribed by your dermatologist or physician. Swallow the capsule whole with a glass of water. Do not crush, chew, or open the capsule. While SB technology reduces food dependencies, taking the capsule with or after a meal is recommended for maximum comfort and optimal absorption. Complete the full prescribed course even if symptoms resolve early.
Storage
Store in a cool, dry, and dark place away from direct sunlight, heat, and moisture. Store at a controlled room temperature below 30°C. Protect from humidity. Keep out of reach and sight of children.
