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Nintedone 100

by Steris Healthcare Pvt. Ltd.

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Nintedanib 100 mg

NINTEDONE 100 (Nintedanib 100 mg Capsules), manufactured by Steris Healthcare, is an oral targeted anti-fibrotic medication and receptor tyrosine kinase inhibitor. Indicated for the management of Idiopathic Pulmonary Fibrosis (IPF), Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD), and other chronic progressive fibrosing Interstitial Lung Diseases (ILDs), it effectively slows down the rate of decline in lung capacity and preserves pulmonary function.

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ManufacturerSteris Healthcare Pvt. Ltd.
Manufacturing qualityWHO-GMP verified
Expiry policyMinimum 3 months
ReviewedClinical review pending

Medicine information

Uses & overview

NINTEDONE 100 by Steris Healthcare delivers 100 mg of Nintedanib, a clinically proven triple angiokinase inhibitor formulated to slow the progression of chronic fibrosing lung diseases. Pulmonary fibrosis causes progressive thickening and scarring of the delicate lung air sacs, impairing oxygen transfer to the bloodstream. NINTEDONE 100 acts directly at the cellular level by blocking specific growth factor signalling pathways responsible for the proliferation, migration, and transformation of lung fibroblasts into scar tissue.

How to use

Take 1 capsule of NINTEDONE 100 twice daily (approximately 12 hours apart), or strictly as prescribed by your pulmonologist or physician. Swallow the capsule whole with a glass of water during or immediately after a meal to enhance absorption and minimize gastrointestinal side effects like nausea or diarrhea. Do not crush, chew, or open the capsule. If a dose is missed, skip the missed dose and resume your scheduled timing—never double up on doses.

Storage

Store in a cool, dry place away from direct sunlight, heat, and moisture. Maintain at a controlled room temperature below 25°C. Do not freeze. Keep the capsules inside their original blister packaging until use to protect from ambient humidity. Keep out of reach and sight of children.

Important guidance

Safety advice

Check with your doctor
AlcoholConsult your doctor

Avoid consuming alcohol during treatment with NINTEDONE 100. Both alcohol and Nintedanib are metabolized by the liver, and concurrent use increases the risk of liver damage and elevated hepatic enzymes.

PregnancyConsult your doctor

NINTEDONE 100 can cause fetal harm, embryofetal lethality, and birth defects. Highly effective contraception must be used during treatment and for at least 3 months following the final dose. Female patients of childbearing potential must undergo pregnancy testing prior to initiating treatment.

BreastfeedingConsult your doctor

It is unknown if Nintedanib passes into human breast milk. Due to potential serious risks to nursing infants, breastfeeding must be discontinued during treatment with NINTEDONE 100.

DrivingConsult your doctor

NINTEDONE 100 may cause dizziness or gastrointestinal upset in some patients. Exercise caution when driving or operating heavy machinery until you know how the drug affects you.

KidneyConsult your doctor

Generally safe in mild to moderate renal impairment. Patients with severe renal impairment should be monitored closely by their specialist due to limited clinical data.

LiverConsult your doctor

Contraindicated in patients with moderate to severe hepatic impairment (Child-Pugh B or C). Liver Function Tests (ALT, AST, Bilirubin) must be evaluated before starting therapy and monitored periodically during treatment.

Clinical review pending

This page uses verified catalogue facts and responsible medicine-information rules. It supports awareness and does not replace a doctor's advice.

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