Medicine information
Uses & overview
REMINIL AM 2.5/5 by Steris Healthcare brings together two complementary, evidence-based cardiovascular agents: low-dose Ramipril (2.5 mg) and Amlodipine (5 mg). Formulated for precise titration and smooth 24-hour blood pressure control, this fixed-dose synergistic combination targets hypertension through dual vascular pathways—suppressing vasoconstrictive hormone production while relaxing arterial smooth muscle to reduce systemic vascular resistance and cardiac workload. Key Ingredients & Clinical Benefits: Ramipril (2.5 mg): A potent Angiotensin-Converting Enzyme (ACE) inhibitor that blocks the conversion of angiotensin I to the vasoconstrictor angiotensin II. It relaxes arterial walls, lowers aldosterone secretion, reduces blood pressure, and offers cardiac and renal vascular protection. Amlodipine (5 mg): A long-acting dihydropyridine Calcium Channel Blocker (CCB) that selectively inhibits calcium ion influx into vascular smooth muscle and heart cells. It induces arterial vasodilation, decreases peripheral vascular resistance, and improves myocardial perfusion. Key Uses & Clinical Benefits: Balanced 24-Hour Blood Pressure Control: Provides smooth, continuous blood pressure reduction over a full 24-hour cycle while minimizing dose-dependent side effects. Dual Mechanism of Action: Combines systemic vasodilation with neurohormonal blockade for optimal arterial compliance and endothelial support. Target Organ Protection: Reduces hypertensive stress on delicate microvascular structures in the heart, kidneys, and brain, lowering long-term risks of stroke and heart attack. Reduces Peripheral Edema: The ACE inhibitor component (Ramipril) counteracts venodilatory imbalance, helping reduce the incidence of ankle swelling (pedal edema) commonly associated with calcium channel blocker monotherapy. Convenient Single-Tablet Regimen: Replaces two separate daily cardiovascular medications with a single, easy-to-swallow fixed-dose tablet, improving patient compliance.
How to use
Take 1 tablet of REMINIL AM 2.5/5 once daily, with or without food (preferably in the morning), or strictly as prescribed by your cardiologist or physician. Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet. Try to take your dose at the same time every day to maintain steady blood pressure control. Do not stop taking the medication abruptly without medical guidance.
Storage
Store in a cool, dry, and dark place away from direct sunlight, heat, and moisture. Store at a controlled room temperature below 30°C. Keep out of reach and sight of children.
