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Sacusmart 25

by Steris Healthcare Pvt. Ltd.

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Sacubitril 12 mg + Valsartan 13 mg

SACUSMART 25 (Sacubitril 12 mg & Valsartan 13 mg Tablets), manufactured by Steris Healthcare, is an innovative Angiotensin Receptor-Neprilysin Inhibitor (ARNI) combination therapy. It is indicated for the treatment of chronic heart failure with reduced ejection fraction (HFrEF) in adult patients, helping reduce the risk of cardiovascular death and heart failure hospitalization while improving overall cardiac function.

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ManufacturerSteris Healthcare Pvt. Ltd.
Manufacturing qualityWHO-GMP verified
Expiry policyMinimum 3 months
ReviewedClinical review pending

Medicine information

Uses & overview

SACUSMART 25 by Steris Healthcare delivers a precise low-dose combination of two breakthrough cardiovascular agents: Sacubitril (12 mg) and Valsartan (13 mg) in a single co-crystallized complex. Engineered for early treatment initiation and careful dose titration, SACUSMART 25 represents the first-line standard of care for heart failure management, offering superior hemodynamic benefits compared to traditional ACE inhibitor or ARB monotherapy.

How to use

Take 1 tablet of SACUSMART 25 twice daily, with or without food, or strictly as prescribed by your cardiologist or physician. Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet.

Storage

Store in a cool, dry, and dark place away from direct sunlight, heat, and moisture. Store at a controlled room temperature below 30°C. Protect from light and atmospheric moisture. Keep out of reach and sight of children.

Important guidance

Safety advice

Check with your doctor
AlcoholConsult your doctor

Avoid drinking alcohol while taking SACUSMART 25, as alcohol can amplify blood pressure reduction, causing excessive dizziness, lightheadedness, or fainting.

PregnancyConsult your doctor

SACUSMART 25 is strictly contraindicated during pregnancy. Activating RAAS inhibition directly can cause fetal harm, severe renal impairment, and developmental defects during the second and third trimesters.

BreastfeedingConsult your doctor

Do not use SACUSMART 25 while nursing without medical guidance. It is unknown if components pass into human milk, and risks to the infant cannot be excluded.

DrivingConsult your doctor

Exercise caution when driving or operating heavy machinery. Blood pressure reduction may cause initial dizziness or fatigue, particularly when starting therapy or adjusting doses.

KidneyConsult your doctor

Use with caution in patients with renal impairment. Serum creatinine and potassium levels must be monitored periodically during treatment.

LiverConsult your doctor

Use with caution in patients with moderate hepatic impairment. SACUSMART 25 is not recommended for severe liver impairment.

Clinical review pending

This page uses verified catalogue facts and responsible medicine-information rules. It supports awareness and does not replace a doctor's advice.

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