Medicine information
Uses & overview
SEIZMET 500 by Steris Healthcare delivers 500 mg of Metformin Hydrochloride in an immediate-release tablet formulation. As the global cornerstone therapy for managing type 2 diabetes, SEIZMET 500 effectively controls blood glucose levels without stimulating excess pancreatic insulin secretion, minimizing the risk of hypoglycemia. Key Uses & Clinical Benefits: First-Line Glycemic Management: Effectively lowers both fasting and postprandial (post-meal) blood glucose levels to help patients achieve and maintain target HbA1c levels. Inhibits Hepatic Glucose Output: Suppresses liver gluconeogenesis and glycogenolysis, preventing excess glucose production and release into the bloodstream. Enhances Insulin Sensitivity: Increases peripheral glucose uptake and utilization in skeletal muscle and adipose tissues, helping body cells respond more efficiently to endogenous insulin. Reduces Intestinal Glucose Absorption: Decreases the rate of glucose absorption from the gastrointestinal tract following meals. Weight-Neutral & Lipid Benefits: Supports healthy weight management and helps maintain balanced lipid profiles, making it particularly beneficial for overweight or obese diabetic patients. How SEIZMET 500 Works: Metformin activates AMP-activated protein kinase (AMPK) in hepatic tissue, which suppresses gluconeogenesis genes and limits hepatic glucose output. It simultaneously enhances insulin receptor sensitivity in peripheral cells, promoting efficient cellular glucose uptake.
How to use
Take 1 tablet of SEIZMET 500 once or twice daily with or immediately after meals (preferably with breakfast or dinner), or strictly as directed by your physician. Taking the medication with meals helps minimize potential gastrointestinal discomfort. Swallow the tablet whole with a glass of water.
Storage
Store in a cool, dry place away from direct sunlight, light, and moisture. Store at a controlled room temperature below 30°C. Keep out of reach and sight of children.
