Medicine information
Uses & overview
ST GLIPTIN 3D 1000 by Steris Healthcare brings together three highly effective antidiabetic agents: Sitagliptin (100 mg), Metformin Hydrochloride Sustained Release (1000 mg), and Pioglitazone (15 mg). This synergistic triple-action formula addresses the multi-faceted defects of type 2 diabetes—enhancing glucose-dependent insulin secretion, improving insulin sensitivity, and reducing excessive hepatic glucose synthesis. Key Uses & Clinical Benefits: Triple-Action Glycemic Control: Combines DPP-4 inhibition, biguanide, and thiazolidinedione (TZD) actions to achieve optimal HbA1c targets and maintain stable fasting and postprandial glucose levels. Enhances Natural Insulin Production: Sitagliptin (a DPP-4 inhibitor) prolongs the activity of incretin hormones, stimulating physiological insulin release after meals while curbing excess glucagon. Combats Insulin Resistance: Pioglitazone acts as a PPAR-gamma agonist to increase insulin sensitivity in muscle and adipose tissue, promoting efficient cellular glucose uptake. Reduces Liver Glucose Production: Metformin SR decreases hepatic glucose output, reduces intestinal absorption of glucose, and improves peripheral tissue sensitivity. Sustained-Release Delivery: The 1000 mg Sustained Release (SR) Metformin formulation allows for smooth, extended drug delivery throughout the day, minimizing gastrointestinal discomfort. How ST GLIPTIN 3D 1000 Works: Sitagliptin (100 mg): Selectively inhibits the DPP-4 enzyme, boosting GLP-1 and GIP levels to regulate mealtime glucose levels safely. Metformin SR (1000 mg): Decreases hepatic gluconeogenesis and optimizes peripheral cell response to circulating insulin. Pioglitazone (15 mg): Targets insulin resistance directly at the receptor level in fat and muscle tissue.
How to use
Take 1 tablet of ST GLIPTIN 3D 1000 daily with food (preferably during or immediately after breakfast or your main meal) or as directed by your physician. Swallow the tablet whole with water. Do not crush, chew, or break the tablet, as doing so will disrupt the sustained-release mechanism of the Metformin component.
Storage
Store in a cool, dry place away from direct sunlight, light, and moisture. Store at a controlled room temperature below 30°C. Keep out of reach and sight of children.
