Medicine information
Uses & overview
TELMISTRUM TRIO 6.25 by Steris Healthcare delivers a potent, synergistic triple-drug therapy combining an Angiotensin II Receptor Blocker (Telmisartan 40 mg), a dual L/N-type Calcium Channel Blocker (Cilnidipine 10 mg), and a thiazide-like diuretic (Chlorthalidone 6.25 mg). Engineered for round-the-clock cardiovascular control, this triple formulation targets high blood pressure across three distinct physiological pathways, reducing vascular resistance, preventing volume overload, and providing comprehensive organ protection. Key Ingredients & Clinical Benefits: Telmisartan (40 mg): An Angiotensin II Receptor Blocker (ARB) with a long duration of action (24-hour half-life). It blocks the vasoconstrictive effects of angiotensin II, relaxing blood vessels, lowering vascular resistance, and protecting renal and cardiac tissues. Cilnidipine (10 mg): A unique dual L/N-type Calcium Channel Blocker (CCB). By blocking L-type channels in blood vessels and N-type channels on sympathetic nerve terminals, it causes smooth vasodilation without causing reflex tachycardia or peripheral pedal edema (ankle swelling). Chlorthalidone (6.25 mg): A long-acting, thiazide-like diuretic that promotes sodium and water excretion from the kidneys. It reduces intravascular fluid volume and enhances the blood pressure-lowering effects of Telmisartan and Cilnidipine. Key Uses & Clinical Benefits: Triple-Action Synergistic Control: Provides robust 24-hour control over severe, uncontrolled, or resistant high blood pressure. Reduces Cardiovascular Risks: Significantly lowers the risk of hypertension-related complications, including stroke, heart attack, and heart failure. Cardio-Protective & Reno-Protective: Cilnidipine dilates both afferent and efferent renal arterioles, shielding the kidneys from high-pressure injury, while Telmisartan reduces cardiovascular remodeling. Minimal Side-Effect Profile: The inclusion of Cilnidipine reduces the risk of pedal edema commonly caused by traditional calcium channel blockers, while low-dose Chlorthalidone minimizes metabolic disturbances. Improved Patient Adherence: Replaces three separate daily blood pressure medications with a single, convenient fixed-dose combination tablet.
How to use
Take 1 tablet of TELMISTRUM TRIO 6.25 once daily, with or without food (preferably in the morning after breakfast), or strictly as prescribed by your cardiologist or physician. Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet. Try to take your medication at the same time every day to maintain steady blood pressure control. Do not stop taking the tablet suddenly without consulting your doctor.
Storage
Store in a cool, dry, and dark place away from direct sunlight, heat, and moisture. Store at a controlled room temperature below 30°C. Keep out of reach and sight of children.
