Prulifloxacin 600 mg Uses, Dosage & Side Effects

Introduction

Prulifloxacin 600 mg, sold under the brand name PRULITECH 600, is a broad-spectrum oral antibiotic used to treat various bacterial infections. prulifloxacin 600 mg uses is especially effective against infections of the urinary tract, respiratory system, and gastrointestinal tract. As a fluoroquinolone prodrug, it converts into ulifloxacin in the body, offering potent antibacterial action with convenient once-daily dosing.

What is Prulifloxacin 600 mg (PRULITECH 600)?

Prulifloxacin 600 mg, marketed as PRULITECH 600, is a fluoroquinolone-class antibiotic used to treat a range of bacterial infections. It is a prodrug that is rapidly converted into ulifloxacin, the active form, after oral administration. This medication is primarily indicated for urinary tract infections, respiratory tract infections, and gastrointestinal infections.

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Composition of PRULITECH 600

• Active Ingredient: Prulifloxacin – 600 mg
• Form: Film-coated tablet
• Route of Administration: Oral

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Prulifloxacin 600 mg uses

Prulifloxacin is effective against a wide spectrum of gram-positive and gram-negative bacteria. It is prescribed for:

• Urinary Tract Infections (UTIs) – including uncomplicated and complicated UTIs
• Chronic Bronchitis – acute exacerbations in chronic bronchitis
• Respiratory Tract Infections – such as community-acquired pneumonia
• Gastrointestinal Infections – including traveler’s diarrhea
• Prostatitis – bacterial inflammation of the prostate gland

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Prulifloxacin 600 mg Dosage and Administration

• Usual Adult Dose:
  One tablet (600 mg) once daily with or without food, as directed by the physician.
• Duration of Therapy:
  Typically ranges from 5 to 10 days, depending on the type and severity of infection.
• Important Notes:
  • Always follow the doctor’s instructions.
  • Do not skip or stop the medication prematurely, even if symptoms improve.
  • Ensure adequate hydration during the treatment.

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Mechanism of Action

Prulifloxacin acts by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes necessary for bacterial DNA replication, transcription, and repair. By disrupting these processes, the drug effectively kills susceptible bacteria.

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Side Effects of Prulifloxacin 600 mg

Like all medications, Prulifloxacin may cause side effects. Common and rare side effects include:

Common Side Effects:

• Nausea
• Diarrhea
• Headache
• Abdominal pain
• Dizziness

Rare but Serious Side Effects:

• Tendonitis or tendon rupture
• Peripheral neuropathy
• QT interval prolongation
• Allergic reactions (rash, itching, swelling)

Seek immediate medical attention if you notice:

• Difficulty breathing
• Severe dizziness
• Irregular heartbeat
• Joint or muscle pain

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Precautions and Warnings

• Avoid in Children: Not recommended for use in individuals under 18 years.
• Pregnancy and Breastfeeding: Use only if clearly needed and prescribed.
• CNS Disorders: Use with caution in patients with epilepsy or CNS disorders.
• Sun Sensitivity: Avoid prolonged exposure to sunlight or UV rays.

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Drug Interactions

Inform your doctor if you are using any of the following:

• Antacids containing aluminum/magnesium
• Iron or zinc supplements
• Warfarin (increased bleeding risk)
• Theophylline or caffeine (increased stimulation)
• Nonsteroidal anti-inflammatory drugs (NSAIDs)

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Storage Instructions

• Store in a cool, dry place below 25°C.
• Keep away from direct sunlight and moisture.
• Keep out of reach of children.

Why PRULITECH 600 mg is Better Than Other Brands

1. Manufactured by Steris Healthcare Pvt. Ltd.
   PRULITECH 600 is a high-quality formulation from Steris Healthcare Pvt. Ltd., a reputed pharmaceutical company known for its WHO-GMP and ISO-certified manufacturing practices. The brand is trusted for its commitment to quality, safety, and efficacy.
2. Accurate Composition & Purity
   Each tablet of PRULITECH 600 contains Prulifloxacin 600 mg, carefully formulated to ensure accurate dosing, high purity, and consistent performance across batches.
3. Excellent Bioavailability
   PRULITECH 600 ensures rapid absorption and efficient conversion into ulifloxacin—the active form—providing a quicker and more sustained antibacterial effect compared to many other generic brands.
4. Convenient Once-Daily Dosing
   With a simple once-a-day dosing regimen, PRULITECH 600 enhances patient adherence and simplifies treatment plans, especially in outpatient settings.
5. Broad-Spectrum Antibacterial Coverage
   Effective against both gram-positive and gram-negative bacteria, PRULITECH 600 is a versatile choice for treating urinary tract infections, bronchitis, gastrointestinal infections, and more.

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FAQs – Prulifloxacin 600 mg

Q1: Is Prulifloxacin 600 mg safe for kidney patients?
A: Dose adjustment may be required in patients with renal impairment. Consult your physician

Q2: Can I take Prulifloxacin on an empty stomach?
A: Yes, but taking it with food may reduce gastrointestinal side effects.

Q3: How quickly does Prulifloxacin start working?
A: Improvement is usually seen within 48–72 hours, but the full course must be completed.

Q4: Can Prulifloxacin be used for COVID-19 or viral infections?
A: No, it is effective only against bacterial infections, not viruses.

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Conclusion

PRULITECH 600 (Prulifloxacin 600 mg) is a highly effective fluoroquinolone antibiotic with broad-spectrum antibacterial activity.Prulifloxacin 600 mg uses is trusted for its once-daily dosing, good patient compliance, and high efficacy in treating respiratory, urinary, and gastrointestinal infections. Like all antibiotics, it should be used responsibly under the guidance of a healthcare professional to avoid resistance and ensure optimal treatment outcomes.